Anti-CCN2 / CTGF Reference Antibody (pamrevlumab)

• Catalog Number: orb1818470
• Category: Antibodies
• Description: Recombinant Antibody
• Clonality: Monoclonal
• Tested applications: ELISA, FC
• Reactivity: Human, Mouse, Rabbit, Rat
• Isotype: IgG1
• Antibody Type: Primary Antibody
• Concentration: 1mg/ml
• Form/Appearance: Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column.
• Conjugation: Unconjugated
• MW: 144.86
• UniProt ID: P29279
• Protein Sequence: CCN2 / CTGF
• Expression System: CHO Cell
• Endotoxins: < 0.001EU/μg,determined by LAL method.
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Alternative names: CCN family member 2, Cellular communication networ
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

The purity of Anti-CCN2 / CTGF Reference Antibody (pamrevlumab) is more than 100%, determined by SEC-HPLC.

Immobilized human CTGF His at 2 µg/mL can bind Anti-CCN2 / CTGF Reference Antibody (pamrevlumab), EC50=0.006105 µg/mL.

Anti-CCN2 / CTGF Reference Antibody (pamrevlumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%

Pamrevlumab inhibited the tumor growth of COLO205 on Balb/c nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 39% at 40 mpk at D31.