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    AGO1 antibody

    Catalog Number: orb67054

    DispatchUsually dispatched within 5-10 working days.
    $ 527.00
    Catalog Numberorb67054
    CategoryAntibodies
    DescriptionRabbit polyclonal to AGO1.Argonaute1 (AGO1) is also known as Eukaryotic translation initiation factor 2C 1 (EIF2C1), which is amember of the Argonaute family of proteins that play a role in RNA interference. AGO1 is highly basic,and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in shortinterfering-RNA-mediated gene silencing. AGO1 binds to short RNAs such as microRNAs (miRNAs)or short interfering RNAs (siRNAs), and represses the translation of mRNAs complementary to them.AGO1 lacks endonuclease activity and does not appear to cleave target mRNAs. AGO1 is alsorequired for transcriptional gene silencing (TGS) of promoter regions which are complementary tobound short antigene RNAs
    Species/HostRabbit
    ClonalityPolyclonal
    Tested applicationsWB
    ReactivityHuman
    ImmunogenN-terminal region of human AGO1
    Dilution rangeWB:1:1000-1:5000
    PurityAffinity purification
    ConjugationUnconjugated
    MW97
    UniProt IDQ9UL18
    Storage-20°C
    Buffer/Preservatives0.01% NaN3
    Alternative namesanti-AGO1 antibody,anti-Protein argonaute1 antibod
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    NoteFor research use only
    Expiration Date12 months from date of receipt.
    AGO1 antibody

    Western blot of total cell extracts from human K562 using AGO1 antibody

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