Adrenomedullin (13-52) peptide

SKU: orb216430

Description

Adrenomedullin (13-52) peptide

Images & Validation

• Application Notes:
  This adrenomedullin fragment possessed vasodilatory activity. It has been suggested to modulate receptor-mediated, but not voltage-dependent, pulmonary vascular contraction by influencing Ca²⁺ influx. Therefore, it has been proposed that hADM (13-52) acts as an endothelium-dependent vasodilator agent in the pulmonary vascular bed of the rat. Furthermore, this compound may act as a modulator of the vascular phases of inflammation.

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Key Properties

• Source: Synthetic
• CAS Number: 154765-05-6
• MW: 4533.17
• Purity: > 95%
• Formula: C₂₀₀H₃₀₈N₅₈O₅₉S₂
• Protein Sequence: H-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge Cys16-Cys21)

Storage & Handling

• Storage: Shipped at 4°C. Store at -20°C for one year.
• Form/Appearance: Lyophilized powder
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only