4-1BB antibody

• Catalog Number: orb613965
• Category: Antibodies
• Description: Rat monoclonal antibody to 4-1BB
• Species/Host: Rat
• Clonality: Monoclonal
• Clone Number: LOB12.3
• Tested applications: FC
• Reactivity: Mouse
• Isotype: IgG2a
• Immunogen: This antibody was generated by immunizing rats with recombinant CD137-Fc fusion protein.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: 4-1BB
• UniProt ID: P20334
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: CD137; TNFRSF9; 41BB; 4-1BBL Ligand; Tumor necrosi
• Note: For research use only
• Application notes: This antibody can be used to detect mouse 4-1BB (CD137). In its original rat IgG1 format, this antibody had agonistic effect and prolonged survival of mice bearing CT26 or A31 tumors. In the original publication another clone LOB12 disclosed which has a rat IgG2a isotype. This has led to some confusion in the literature with regards to the original isotype of LOB12 and LOB12.3. We offer this antibody in both formats as well as murine versions so that researchers may choose the isotype most appropriate for their assays.
• Expiration Date: 12 months from date of receipt.