187-1, N-WASP inhibitor TFA

SKU: orb1981674

Description

187-1, N-WASP Inhibitor TFA is a cyclic peptide that allosterically inhibits neural Wiskott-Aldrich syndrome protein (N-WASP), maintaining its autoinhibited state. With an IC₅₀ of 2 µM, it blocks PIP₂-induced actin polymerization and Arp2/3 complex activation. This inhibitor is a valuable tool for studying cytoskeletal dynamics in cell migration, endocytosis, and cancer metastasis research in vitro.

Research Area

Immunology & Inflammation; Musculoskeletal & Connective Tissue Research; Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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Target	Arp2/3 Complex
MW	1898.13
Formula	C₉₈H₁₂₃F₃N₁₈O₁₈

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Arp2/3 Complex

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Protocol Information

Protein Handling and Storage Guide

Protein Handling Guide

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