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187-1, N-WASP inhibitor TFA

SKU: orb1981674

Description

187-1, N-WASP Inhibitor TFA is a cyclic peptide that allosterically inhibits neural Wiskott-Aldrich syndrome protein (N-WASP), maintaining its autoinhibited state. With an IC₅₀ of 2 µM, it blocks PIP₂-induced actin polymerization and Arp2/3 complex activation. This inhibitor is a valuable tool for studying cytoskeletal dynamics in cell migration, endocytosis, and cancer metastasis research in vitro.

Research Area

Signal Transduction

Images & Validation

Key Properties

TargetArp2/3 Complex
Molecular Weight1898.13

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

187-1, N-WASP inhibitor TFA (orb1981674)

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