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Z-IETD-FMK

SKU: orb1222522

Description

MDK4982, also known as Z-IETD-FMK, is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B., The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. MDK4982 effectively inhibits influenza virus-induced apoptosis in HeLa cells. MDK4982 also inhibits granzyme B. MDK4982 has CAS#210344-98-2.

Images & Validation

Key Properties

CAS Number210344-98-2
MW654.68
Purity>98% (HPLC)
FormulaC30H43FN4O11
SMILESCC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1
TargetHistamine Receptor
SolubilityDMSO : 125 mg/mL 190.93 mM; H2O : < 0.1 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Z-IE(OMe)TD(OMe)-FMK | Granzyme B Inhibitor III | Z-IETD-FMK

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Protocol Information

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500 mg
100 mg
200 mg
2 mg
$ 310.00
5 mg
$ 440.00
10 mg
$ 700.00
25 mg
$ 1,120.00