XL-184 (Cabozantinib,BMS907351)

• Catalog Number: orb154637
• Category: Small Molecules
• Description: XL184 (Cabozantinib) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
• CAS Number: [849217-68-1]
• MW: 501.51
• SMILES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F
• Formula: C₂₈H₂₄FN₃O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.