XIAP Antibody

• Catalog Number: orb1731187
• Category: Antibodies
• Description: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: Recombinant protein of mouse XIAP
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000
• Conjugation: Unconjugated
• MW: Calculated MW: 56 kDa; Observed MW: 53 kDa
• Entrez: 11798
• UniProt ID: Q60989
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-
• Note: For research use only
• Expiration Date: 12 months from date of receipt.