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Vimirogant hydrochloride
Catalog Number: orb1685745
| Catalog Number | orb1685745 |
|---|---|
| Category | Small Molecules |
| Description | Vimirogant hydrochloride |
| Purity | 98% |
| Formula | C27H36ClF3N4O3S |
| Biological Activity | Vimirogant (VTP-43742) hydrochloride is an orally active, selective RORγt inhibitor (IC50: 17 nM, Ki: 3.5 nM) that is more than 1000 times more selective than RORα and RORβ. Vimirogant hydrochloride inhibits Th17 differentiation and IL-17A secretion in mouse spleen cells with an IC50 value of 57 nM and does not affect the differentiation of Th1, Th2 or Treg cells. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
