VDAC1 antibody

• Catalog Number: orb150786
• Category: Antibodies
• Description: Mouse monoclonal to VDAC1 (ATTO-488). Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis..
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: S152B-23
• Tested applications: ICC, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG2a
• Immunogen: Fusion protein amino acids 1-283 (full-length) of human VDAC1. Mouse: 98% identity (279/283 amino acids identical). Rat: 98% identity (279/283 amino acids identical) > 60% identity with VDAC2 and VDAC3.
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000)
• Conjugation: ATTO-488
• MW: 30kDa
• Target: VDAC1
• Entrez: 7416
• UniProt ID: P21796
• NCBI: NP_003365.1
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated
• Alternative names: Voltage Dependent Anion Channel 1 antibody, Porin
• Note: For research use only
• Application notes: 1 µg/ml of SMC-456 was sufficient for detection of VDAC1 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.