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VCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated
Catalog Number: orb1961878
| Catalog Number | orb1961878 |
|---|---|
| Category | Proteins |
| Description | VCAM-1 (CD106, INCAM-110) is a cell adhesion molecule and a member of the immunoglobulin superfamily. It's important function is a recognition of cell-cell. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
| Tag | C-Avi-6xHis |
| Purity | 98.00% |
| MW | 90-125 KDa (reducing condition) |
| UniProt ID | P19320 |
| Protein Sequence | Phe25-Glu698 |
| Expression System | HEK293 Cells |
| Biological Origin | Human |
| Biological Activity | VCAM-1 (CD106, INCAM-110) is a cell adhesion molecule and a member of the immunoglobulin superfamily. It's important function is a recognition of cell-cell. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation。 |
| Expression Region | Phe25-Glu698 |
| Storage | -20°C |
| Note | For research use only |
| Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Expiration Date | 6 months from date of receipt. |
