VAV1 antibody

• Catalog Number: orb99339
• Category: Antibodies
• Description: Rabbit polyclonal to VAV1.The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins.The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation.This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1.Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication..
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: IHC-P, WB
• Reactivity: Human, Mouse, Rat
• Dilution range: WB:1:500-1:2000,IHC-P:1:50-1:200
• Conjugation: Unconjugated
• Alternative names: anti VAV antibody, anti Vav proto-oncogene antibod
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis on K562 cell lysate using VAV1 antibody