UT-A1 antibody

• Catalog Number: orb152758
• Category: Antibodies
• Description: Rabbit polyclonal to UT-A1 (ATTO-390). UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promoter and expressed in the thin descending limb of Henle, viz. UT-A2. ).
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ICC, IHC, WB
• Reactivity: Mouse, Rat
• Immunogen: Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194)
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000); IHC (1:25)
• Conjugation: ATTO-390
• MW: 97 and 127kDa
• Target: UT-A1
• Entrez: 54302
• UniProt ID: Q62668
• NCBI: NP_062220
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Alternative names: SLC14A2 antibody, FLJ16167 antibody, hUT-A6 antibo
• Note: For research use only
• Application notes: 1 µg/ml of SPC-406 was sufficient for detection of UT-A1 in 20 µg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.