USP14 antibody

• Catalog Number: orb134977
• Category: Antibodies
• Description: Rabbit polyclonal to USP14. Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 889CT6.2.1
• Tested applications: WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG1
• Immunogen: Recombinant Protein
• Dilution range: WB: 1:1000
• Form/Appearance: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
• Conjugation: Unconjugated
• MW: 56069
• Target: USP14
• UniProt ID: P54578
• NCBI: NP_005142.1, NP_001032411.1
• Alternative names: anti USP14 antibody, anti TGT antibody, anti Ubiqu
• Note: For research use only
• Expiration Date: 12 months from date of receipt.