You have no items in your shopping cart.
Cart summary
URAT1&XO inhibitor 2
Catalog Number: orb1944318
| Catalog Number | orb1944318 |
|---|---|
| Category | Small Molecules |
| Description | Compound BDEO (URAT1&XO inhibitor 2) serves as a dual-action inhibitor targeting both xanthine oxidase (XO) and URAT1, demonstrating an IC50 value of 3.3 μM for XO inhibition. It effectively impedes uric acid uptake in HEK293 cells with URAT1 expression, evidenced by a Ki of 0.145 μM. In hyperuricemic mice models, the compound has been shown to reduce serum urate levels and uric acid excretion, indicating potential utility for hyperuricemia research [1]. |
| CAS Number | 1239488-96-0 |
| Purity | 98.00% |
| MW | 322.15 |
| SMILES | C(\CC1=CC=C(Br)C=C1)(=N\O)/C2=C(O)C=C(O)C=C2 |
| Formula | C14H12BrNO3 |
| Biological Activity | Compound BDEO (URAT1&XO inhibitor 2) serves as a dual-action inhibitor targeting both xanthine oxidase (XO) and URAT1, demonstrating an IC50 value of 3.3 μM for XO inhibition. It effectively impedes uric acid uptake in HEK293 cells with URAT1 expression, evidenced by a Ki of 0.145 μM. In hyperuricemic mice models, the compound has been shown to reduce serum urate levels and uric acid excretion, indicating potential utility for hyperuricemia research [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
