ULBP2 Antibody

• Catalog Number: orb636631
• Category: Antibodies
• Description: This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6
• Target: ULBP2
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: Mouse IgG1
• Conjugation: Unconjugated
• Reactivity: Human
• Concentration: Approximately 1mg/ml (varies from batch to batch). Please inquire for precise concentration.
• Buffer/Preservatives: Purified antibody in PBS with 0.05% sodium azide
• Immunogen: Purified recombinant fragment of human ULBP2 (AA: 26-216) expressed in E. Coli.
• UniProt ID: Q9BZM5
• MW: Expected MW is 47.6 kDa
• Tested applications: ELISA, FC, ICC, WB
• Dilution range: WB: 1/500 - 1/2000 ICC (Immunocytochemistry): 1/500 - 1/2000 FC: 1/200 - 1/400 ELISA: 1/10000
• Antibody Type: Primary Antibody
• Clone Number: 1F12C2
• Storage: 4°C; -20°C for long term storage
• Alternative names: N2DL2; RAET1H; RAET1L; NKG2DL2; ALCAN-alpha
• Note: For research use only
• Entrez: 80328
• Expiration Date: 12 months from date of receipt.

Western blot analysis using ULBP2 mAb against HEK293 (1) and ULBP2 (AA: 26-216)-hIgGFc transfected HEK293 (2) cell lysate

Western blot analysis using ULBP2 mAb against human ULBP2 (AA: 26-216) recombinant protein. (Expected MW is 47.6 kDa)

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)

Flow cytometric analysis of Hela cells using ULBP2 mouse mAb (green) and negative control (red)