ULBP2 Antibody

SKU: orb636631

Description

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6

Research Area

Cell Biology

Images & Validation

• Tested Applications: ELISA, FC, ICC, WB
• Dilution Range: WB: 1/500 - 1/2000 ICC (Immunocytochemistry): 1/500 - 1/2000 FC: 1/200 - 1/400 ELISA: 1/10000
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone No.: B3H34E4
• Immunogen: Purified recombinant fragment of human ULBP2 (AA: 26-216) expressed in E. Coli.
• Target: ULBP2
• Molecular Weight: Expected MW is 47.6 kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: 4°C; -20°C for long term storage
• Buffer/Preservatives: Purified antibody in PBS with 0.05% sodium azide
• Concentration: Approximately 1mg/ml (varies from batch to batch). Please inquire for precise concentration.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

N2DL2; RAET1H; RAET1L; NKG2DL2; ALCAN-alpha

Quick Database Links

Gene Symbol

ULBP2

UniProt

Q9BZM5

NCBI Gene ID

80328