UHRF1 PHD inhibitor MLD4

SKU: orb1785936

Description

UHRF1 PHD inhibitor MLD4 is a specific compound that selectively inhibits the UHRF1-histone interaction (IC50=12.4 uM), targets the PHD finger of UHRF1, specifically disrupting histone H3 arginine 2 interactions with the PHD finger.UHRF1 PHD inhibitor MLD4 inhibited binding between H3K9me3(FAM) and UHRF1 with IC50 of 24-26 uM, displace UHRF1-histone H3 binding in cells.

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Key Properties

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CAS Number	922067-76-3
MW	416.522
Purity	>98%
Formula	C₂₂H₃₂N₄O₄

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Disclaimer	For research use only

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