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Catalog Number | orb1730743 |
---|---|
Category | Antibodies |
Description | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. |
Species/Host | Rabbit |
Clonality | Monoclonal |
Tested applications | ICC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | Rabbit IgG |
Immunogen | Recombinant protein of human UBE3A |
Concentration | 1mg/ml |
Dilution range | IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200 |
Conjugation | Unconjugated |
MW | Calculated MW: 101 kDa; Observed MW: 101 kDa |
Entrez | 7337 |
UniProt ID | Q05086 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin |
Alternative names | Ubiquitin-protein ligase E3A; UBE3A; E6AP; EPVE6AP Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ICC, IP, WB | |
Human, Mouse, Rat | |
Rabbit | |
Monoclonal | |
Unconjugated |
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