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UBE2T Protein, Human, Recombinant (His)
Catalog Number: orb1955467
| Catalog Number | orb1955467 |
|---|---|
| Category | Proteins |
| Description | Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers, representing an attractive target for the development of inhibitors. Notably, UBE2T locates at 1q32.1, and the gain of 1q is frequently observed in a variety of cancers. For instance, UBE2T serves an important role in the growth of bladder cancer cells, and may be considered as a potential biomarker and therapeutic target for bladder cancer. |
| Tag | C-His |
| Purity | 98.00% |
| MW | 23.9 kDa (predicted) |
| UniProt ID | Q9NPD8 |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers, representing an attractive target for the development of inhibitors. Notably, UBE2T locates at 1q32.1, and the gain of 1q is frequently observed in a variety of cancers. For instance, UBE2T serves an important role in the growth of bladder cancer cells, and may be considered as a potential biomarker and therapeutic target for bladder cancer. |
| Expression Region | A DNA sequence encoding the human UBE2T (Q9NPD8) (Met1-Val197) was fused with a polyhistidine tag at the C-terminus. Predicted N terminal: Met |
| Storage | -20°C |
| Note | For research use only |
| Application notes | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Expiration Date | 6 months from date of receipt. |
