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Catalog Number | orb1957251 |
---|---|
Category | Small Molecules |
Description | UBE2D1 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | Approxiamtely 18.3 kDa |
Biological Activity | Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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