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Catalog Number | orb1961015 |
---|---|
Category | Small Molecules |
Description | UBA5 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 14&40-60 KDa, reducing conditions |
Biological Activity | UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localizes to the nucleus in presence of SUMO2. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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