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Catalog Number | orb1961215 |
---|---|
Category | Proteins |
Description | GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II. |
Tag | C-6xHis |
Purity | 98.00% |
MW | 40 KDa (reducing condition) |
UniProt ID | Q13630 |
Protein Sequence | Met1-Lys321 |
Expression System | E. coli |
Biological Origin | Human |
Biological Activity | GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II. |
Expression Region | Met1-Lys321 |
Storage | -20°C |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human TSTA3(Met1-Lys321) was fused with the C-terminal His Tag and expressed in E. coli. |