TSC1 antibody

• Catalog Number: orb106930
• Category: Antibodies
• Description: Rabbit polyclonal to TSC1. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Clone Number: RB42204
• Tested applications: WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Dilution range: WB: 1:1000
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• MW: 129767
• Target: TSC1
• UniProt ID: Q92574
• NCBI: NP_001155899.1, NP_001155898.1, NP_000359.1
• Alternative names: anti TSC1 antibody, anti KIAA0243 antibody, anti T
• Note: For research use only
• Expiration Date: 12 months from date of receipt.