TrpV3 antibody

• Catalog Number: orb148707
• Category: Antibodies
• Description: Mouse monoclonal to TrpV3 (HRP). The TRPV3 protein belongs to a family of non-selective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermo sensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: N15/39 (Formerly sold as S15-39)
• Tested applications: AM, ICC, IHC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG2a
• Immunogen: Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000), IHC (1:1000), ICC/IF (1:100)
• Conjugation: HRP
• MW: 70kDa
• Target: TRPV3
• Entrez: 497948
• UniProt ID: Q4QYD9
• NCBI: NP_001020928
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Alternative names: VRL3 antibody, vanilloid receptor 2 antibody, tran
• Note: For research use only
• Application notes: 1 µg/ml of SMC-334 was sufficient for detection of TrpV3 in 10 µg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody
• Expiration Date: 12 months from date of receipt.