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Catalog Number | orb148859 |
---|---|
Category | Antibodies |
Description | Mouse monoclonal to TrpC7 (FITC). Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway. TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure.. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | N64A/36 (Formerly sold as S64A-36) |
Tested applications | AM, ICC, IHC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | IgG1 |
Immunogen | Synthetic peptide amino acids 845-862 of human TRPC7 |
Concentration | 1 mg/ml |
Dilution range | WB (1:1000), IHC (1:1000), ICC/IF (1:100) |
Conjugation | FITC |
MW | 100kDa |
Target | TRPC7 |
Entrez | 57113 |
UniProt ID | Q9HCX4 |
NCBI | NP_065122.1 |
Storage | Conjugated antibodies should be stored at 4°C |
Buffer/Preservatives | PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated |
Alternative names | TRP7 antibody, KNP3 antibody, TRPM2 antibody, tran Read more... |
Note | For research use only |
Application notes | 1 µg/ml of SMC-343 was sufficient for detection of TrpC7 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Expiration Date | 12 months from date of receipt. |
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