TrpC5 antibody

• Catalog Number: orb148875
• Category: Antibodies
• Description: Mouse monoclonal to TrpC5 (Biotin). Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is a subtype of the TRPC family of mammalian transient receptor potential ion channels. Homo-multimeric TRPC5 and hetero-multimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin. This activation probably plays a role in rheumatoid arthritis. It has also been recently found to be involved in the action on anaesthetics such as chloroform, halothane and propofol..
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: N67/15 (Formerly sold as S67-15)
• Tested applications: AM, IHC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: IgG2b
• Immunogen: Synthetic peptide amino acids 827-845 of human TrpC5 (also known as short transient receptor potential channel 5, and Htrp5)
• Concentration: 1 mg/ml
• Dilution range: WB (1:1000), IHC (1:1000), ICC/IF (1:100)
• Conjugation: Biotin
• MW: 110kDa
• Target: TRPC5
• Entrez: 7224
• UniProt ID: Q9UL62
• NCBI: NP_036603.1
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Alternative names: Htrp5 antibody, Short transient receptor potential
• Note: For research use only
• Application notes: 1 µg/ml of SMC-344 was sufficient for detection of TrpC5 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.