Triptophenolide

SKU: orb1304244

Description

Triptophenolide (Hypolide) is a bioactive small molecule isolated from Tripterygium wilfordii Hook. f. It exhibits anti-inflammatory properties and is utilized in research to study inflammatory pathways in both cellular (in vitro) and animal (in vivo) experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 74285-86-2
• MW: 312.40
• Purity: 98.07%
• Formula: C₂₀H₂₄O₃
• SMILES: [H][C@@]12CCc3c(O)c(ccc3[C@@]1(C)CCC1=C2COC1=O)C(C)C
• Target: Androgen Receptor
• Solubility: DMSO:245.00 mg/mL (784.25 mM);Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;10% DMSO+90% Corn Oil:2.50 mg/mL (8.00 mM)

Bioactivity

• Target IC50:
  AR (WT):260 nM|AR (T877A):388 nM|AR (F876L):480 nM

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Triptophenolide, inhibit, Inhibitor, Hypolide, (+)-Triptophenolide, AndrogenReceptor, Androgen Receptor

Compound Identifiers

PubChem CID

173273