TPX-0022(CSF1R-IN-2)

• Catalog Number: orb1089554
• Category: Small Molecules
• Description: TPX-0022 (CSF1R-IN-2) is a potent inhibitor of MET/CSF1R/SRC with enzymatic kinase inhibition IC50s of 0.14 nM, 0.71 nM and 0.12 nM, respectively. TPX-0022 modulates the tumor immune microenvironment in preclinical models.
• CAS Number: [2271119-26-5]
• MW: 409.425
• SMILES: FC1C=CC2=C(C=1C#N)CN(CC)C1C=CN3C(=C(C(N)=N3)C(NC[C@H](C)O2)=O)N=1
• Formula: C₂₀H₂₀FN₇O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.