Torkinib (PP242)

• Catalog Number: orb181304
• Category: Small Molecules
• Description: PP242 is a selective mTOR inhibitor with IC50 of 8 nM; targets both mTOR complexes with > 10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively; also showed slightly weaker activity against BRD4 (Kd= 1.7 uM).
• CAS Number: [1092351-67-1]
• MW: 308.34
• SMILES: N1C2=C(C=C(O)C=C2)C=C1C1C2=C(N)N=CN=C2N(C(C)C)N=1
• Formula: C₁₆H₁₆N₆O
• Note: For research use only
• Expiration Date: 12 months from date of receipt.