TOPORS antibody

• Catalog Number: orb67252
• Category: Antibodies
• Description: Rabbit polyclonal to TOPORS.TOPORS functions as an E3 ubiquitin-protein ligase and an E3 SUMO1-protein ligase. It is a probabletumor suppressor involved in cell growth, cell proliferation and apoptosis. TOPORS regulatesp53/TP53 stability through ubiquitin-dependent degradation. It may regulate chromatin modificationthrough sumoylation of several chromatin modification-associated proteins. It may be involved in DNAdamage-induced cell death through IKBKE sumoylation. Defects in TOPORS are the cause of retinitispigmentosa type 31 P31).
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: C-terminal region of human TOPORS
• Dilution range: WB:1:500-1:1000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 119
• UniProt ID: Q9NS56
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-TOPORS antibody,anti-E3 ubiquitinprotein liga
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela using TOPORS antibody