Tivozanib(AV-951)

• Catalog Number: orb154729
• Category: Small Molecules
• Description: Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met EGFR and IGF-1R.
• CAS Number: [475108-18-0]
• MW: 454.86306
• SMILES: O=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4
• Formula: C₂₂H₁₉ClN₄O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of Tivozanib(AV-951)