Tioconazole

SKU: orb1310895

Description

Tioconazole is an imidazole antifungal agent that disrupts fungal cell membrane integrity by inhibiting ergosterol biosynthesis. It is widely used in research for studying antifungal mechanisms and efficacy in both in vitro assays and in vivo models of fungal infection.

Research Area

Cell Biology, Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 65899-73-2
• MW: 387.71
• Purity: 99.81%
• Formula: C₁₆H₁₃Cl₃N₂OS
• SMILES: C(CN1C=CN=C1)(OCC2=C(Cl)SC=C2)C3=C(Cl)C=C(Cl)C=C3
• Target: Autophagy,Antifection,mTOR,Parasite,Antibiotic,Akt,PI3K,Antifungal
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.16 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:72 mg/mL (185.71 mM);DMSO:50 mg/mL (128.96 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

14-α Demethylase, antimicrobial, antifungal, Antibiotic, Inhibitor, Fungal, inhibit, mycoses, infections, Tioconazole, superficial, yeast, UK 20349, UK20349, UK-20349, Vagistat

Compound Identifiers

PubChem CID

5482