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Catalog Number | orb1304110 |
---|---|
Category | Small Molecules |
Description | THZ1 2HCl |
CAS Number | 2095433-94-4 |
Purity | 98.33% |
MW | 638.98 |
SMILES | O=C(NC1=CC=C(C(NC2=CC(NC3=NC(C4=CNC5=C4C=CC=C5)=C(Cl)C=N3)=CC=C2)=O)C=C1)C=CCN(C)C.Cl.Cl |
Formula | C31H30Cl3N7O2 |
Biological Activity | THZ1 2HCl (THZ1 Dihydrochloride) is a selective, covalent, and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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