TdT Antibody (FITC)

• Catalog Number: orb1993773
• Category: Antibodies
• Description: Terminal deoxynucleotidyl transferase (TdT) is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. It is expressed in restricted populations of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
• Clonality: Monoclonal
• Clone Number: 41A
• Tested applications: FC
• Reactivity: Human
• Isotype: Mouse IgG2a
• Immunogen: His-TdT recombinant protein
• Conjugation: FITC
• Target: TdT
• Entrez: 1791
• UniProt ID: P04053
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: Terminal transferase, DNTT, Terminal addition enzy
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for intracellular analysis of human blood cells after XPerm (fixation and permeabilization reagent, ED7397) permeabilization of cell membrane and using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.