TDG antibody

• Catalog Number: orb67223
• Category: Antibodies
• Description: Rabbit polyclonal to TDG.G/T mismatch-specific thymine DNA glycosylase (TDG) belongs to the TDG/mug DNA glycosylasefamily. TDG removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bondbetween the sugar-phosphate backbone of DNA and the mispaired thymine. TDG also removesthymine from C/T and T/T mispairings with lower activity. In addition, TDG can remove uracil and 5-bromouracil from mispairings with guanine. TDG plays a central role in cellular defense againstgenetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: N-terminal region of human TDG
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 46
• UniProt ID: Q13569
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-TDG antibody,anti-G antibody,anti-T mismatchs
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from (Lane1)mouse thymocytes, (Lane2)human MCF7 and (Lane3)human jurkat cell using TDG antibody