TCPOBOP

SKU: orb1307694

Description

TCPOBOP is a potent and selective agonist of the constitutive androstane receptor (CAR). It is widely used in research to study CAR-mediated hepatocyte proliferation, hepatomegaly, and protection against Fas-induced liver injury in murine models, both in vitro and in vivo.

Research Area

Cell Biology

Key Properties

• CAS Number: 76150-91-9
• MW: 402.06
• Purity: 99.70%
• Formula: C₁₆H₈Cl₄N₂O₂
• SMILES: Clc1cnc(Oc2ccc(Oc3ncc(Cl)cc3Cl)cc2)c(Cl)c1
• Target: Bcl-2 Family
• Solubility: DMSO:25 mg/mL (62.18 mM);10% DMSO+90% Corn Oil:2 mg/mL (4.97 mM)

Bioactivity

• In Vivo:
  TCPOBOP (p.o.; 3 mg/kg; 1-5 days) obviously enhances Liver weight to body weight in LW/BW ratio at 48 hours.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

Bcl-2, Bcl-2 Family, inhibit, Inhibitor, TCPOBOP

Compound Identifiers

PubChem CID

5382