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Catalog Number | orb1960995 |
---|---|
Category | Small Molecules |
Description | TCblR Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 32-58 KDa, reducing conditions |
Biological Activity | CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human CD320(Met1-Tyr229) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
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