SREBP1 antibody

• Catalog Number: orb131771
• Category: Antibodies
• Description: Rabbit polyclonal to SREBP1. Sterol regulatory element-binding protein 1 (SREBP1) is a member of the basic helix-loop-helixleucine zipper (bHLH-Zip) transcription factor family, which is required for lipid homeostasis. SREBP1 regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. SREBP1 binds to the sterol regulatory element 1 (SRE-1) (5-ATCACCCCAC-3), and it has dual sequence specificity binding to both an E-box motif (5-ATCACGTGA-3) and to SRE-1 (5-ATCACCCCAC-3).
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: C-terminal region of human SREBP1
• Concentration: 100 μg/ml BSA
• Dilution range: WB:1:1000-1:3000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 122
• UniProt ID: P36956
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti Sterol regulatory element-binding protein 1 a
• Note: For research use only
• Application notes: WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.; ; Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SREBP1.
• Expiration Date: 12 months from date of receipt.