SOCS6 antibody

• Catalog Number: orb67266
• Category: Antibodies
• Description: Rabbit polyclonal to SOCS6.Suppressor of cytokine signaling 6 (SOCS6) is a member of the SOCS family proteins that form partof a classical negative feedback system that regulates cytokine signal transduction. SOCS6 may be asubstrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomaldegradation of target proteins. SOCS6 regulates the degradation of the tyrosine-phosphorylated KITreceptor by ubiquitination.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: C-terminal region of human SOCS6
• Dilution range: WB:1:500-1:2000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 60
• UniProt ID: O14544
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-SOCS6 antibody,anti-Suppressor of cytokine si
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela(Lane1)