SLC38A1 Antibody (APC)

SKU: orb149843

Description

Mouse monoclonal to SNAT1 (APC). The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. The SNAT1 protein, also designated ATA1 or NAT2 is encoded by the human gene SLC38A1 which maps to chromosome 12q13. 11. SNAT1 is responsible for the transport of glutamine, an intermediate in the synthesis of urea, and may be involved in the generation of glutamate in the retina. SNAT1 protein may be detected in some tissues such as heart, brain and placenta and expression levels are enriched in certain neuronal populations within the CNS. SNAT1 is not present in astrocytes..

Research Area

Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Images & Validation

• Tested Applications: FC, ICC, IF, IHC, WB
• Dilution Range: WB (1:1000)
• Reactivity: Human, Mouse, Rat
• Application Notes:
  1 µg/ml was sufficient for detection of SNAT1 in 20 µg of lysates from neocortical neurons cultured under amino acid starvation conditions and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: N104/32 (Formerly sold as S104-32)
• Immunogen: Fusion protein amino acids 1- 63 of rat SNAT1
• Target: SLC38A1
• Molecular Weight: 50kDa
• Purification: Protein G Purified
• Conjugation: APC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 95.46mM Phosphate, 2.48mM MES and 2mM EDTA
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SNAT1, SLC38A1, amino acids transporter A1, ATA1, NAT2, sodium coupled neutral amino acids transporter 1, Amino acid transporter system A1, N-system amino acid transporter 2, S38A1, SAT1, SNAT 1, Solute carrier family 38 member 1, System A amino acid transporter 1, System N amino acid transporter 1

Quick Database Links

Gene Symbol

SLC38A1

UniProt

Q9JM15

NCBI Gene ID

170567

RefSeq (Protein):NP_620187.1