SNAP25 Antibody

• Catalog Number: orb1730353
• Category: Antibodies
• Description: SNAP25 forms a core complex with the SNARE proteins syntaxin and synaptobrevin to mediate synaptic vesicle fusion with the plasma membrane during Ca2+-dependent exocytosis. This complex is responsible for exocytosis of the neurotransmitter γ-aminobutyric acid (GABA). Neurotransmitter release is inhibited by proteolysis of SNAP25 by botulinum toxins A and E. SNAP25 plays a secondary role as a Q-SNARE involved in endosome fusion; the protein is associated with genetic susceptibility to attention-deficit hyperactivity disorder (ADHD).
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ICC, IP, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human SNAP25
• Dilution range: IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 23 kDa; Observed MW: 23 kDa
• Entrez: 6616
• UniProt ID: P60880
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Alternative names: Synaptosomal-associated protein 25; SNAP-25; Super
• Note: For research use only
• Expiration Date: 12 months from date of receipt.