SNAP 94847 hydrochloride

SKU: orb1299307

Description

SNAP 94847 hydrochloride is a potent and selective MCHR1 antagonist with a Ki of 2.2 nM. This compound is a valuable research tool for investigating the role of the MCH system in energy homeostasis, stress, and sleep regulation in both in vitro and in vivo studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1781934-47-1
• MW: 515.03
• Purity: >99.99% (May vary between batches)
• Formula: C₂₉H₃₃ClF₂N₂O₂
• SMILES: Cl.CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1
• Target: Melanin-concentrating Hormone Receptor (MCHR),GPCR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.71 mM);DMSO:250 mg/mL (485.41 mM)

Bioactivity

• Target IC50:
  MCH1R:2.2 nM(Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SNAP94847, SNAP-94847, SNAP94847 Hydrochloride, SNAP-94847 Hydrochloride, SNAP 94847, SNAP 94847 Hydrochloride, SNAP 94847 hydrochloride, MelaninconcentratingHormoneReceptor, MelaninconcentratingHormoneReceptor(MCHR), Melaninconcentrating Hormone Receptor (MCHR), Melanin concentrating hormone receptor 1, Melanin-concentrating Hormone Receptor, MCHR, MCHR1 (GPR24), MCH1-R, Inhibitor, inhibit, anxiolytic, anxiety, Antidepressant

Compound Identifiers

PubChem CID

56972235