SMAD6 antibody

• Catalog Number: orb67255
• Category: Antibodies
• Description: Rabbit polyclonal to SMAD6.Mothers against decapentaplegic homolog 6 (SMAD6) belongs to the dwarfin/SMAD family. SMAD6 isan antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamilymembers; it has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling bycompeting with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (ISMAD)or antagonistic SMAD. Binds to regulatory elements in target promoter regions.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: middle region of human SMAD6
• Dilution range: WB:1:500-1:1000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 53
• UniProt ID: O43541
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-SMAD6 antibody,anti-Mothers against decapenta
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela(Lane1) and human Jurkat(Lane2) using SMAD6 antibody