SLU-PP-332

SKU: orb1819063

Description

SLU-PP-332 is a pan-ERR agonist with high affinity for ERRα, ERRβ, and ERRγ (EC50: 98, 230, and 430 nM). In skeletal muscle cells, it enhances mitochondrial function, respiration, type IIa fiber formation, and exercise endurance. It shows promise for studying and treating metabolic diseases, muscle dysfunction, and age-related decline.

Research Area

Metabolism Research

Key Properties

• CAS Number: 303760-60-3
• MW: 290.32
• Purity: 98.30% (May vary between batches)
• Formula: C₁₈H₁₄N₂O₂
• SMILES: C(=NNC(=O)C1=CC=C(O)C=C1)C2=CC3=C(C=C2)C=CC=C3
• Target: Estrogen/ progestogen Receptor, Estrogen Receptor/ ERR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.89 mM);DMSO:83.33 mg/mL (287.03 mM)

Bioactivity

• Target IC50:
  ERRβ:230 nM (EC50)|ERRα:98 nM (EC50)|ERRγ:430 nM (EC50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

EstrogenReceptor, Estrogen Receptor, ERRγ, ERRβ, ERRα, progestogenReceptor, progestogen Receptor, SLU-PP 332, SLUPP332, SLU-PP332, SLU-PP-332

Compound Identifiers

PubChem CID

769784