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Catalog Number | orb1956639 |
---|---|
Category | Small Molecules |
Description | SLITL2/VASN Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 61.1 kDa (predicted) |
Biological Activity | Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular smooth muscle cells, and that its expression is developmentally regulated. vasorin It directly binds to transforming growth factor (TGF)-β and attenuates TGF-β signaling in vitro. This suggests that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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