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Catalog Number | orb1960975 |
---|---|
Category | Proteins |
Description | SLAM family member 8 (SLAMF8) is a single-pass type I membrane protein and contains 1 Ig-like C2-type domain. SLAMF8 is a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. SLAMF8 is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. |
Tag | C-6xHis |
Purity | 98.00% |
MW | 34 KDa (reducing condition) |
UniProt ID | Q9P0V8 |
Protein Sequence | Ala23-Asp233 |
Expression System | HEK293 Cells |
Biological Origin | Human |
Biological Activity | SLAM family member 8 (SLAMF8) is a single-pass type I membrane protein and contains 1 Ig-like C2-type domain. SLAMF8 is a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. SLAMF8 is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. |
Expression Region | Ala23-Asp233 |
Storage | -20°C |
Note | For research use only |
Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Expiration Date | 6 months from date of receipt. |
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 24.2 kDa after removal of the signal peptide. The apparent molecular mass of SLAMF8-His is approximately 25-35 kDa due to glycosylation. | |
Mammalian |
> 95% by SDS-PAGE. | |
Recombinant Human SLAMF8 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Ala23-Asp233) of human SLAMF8 (Accession #Q9P0V8) fused with a 6xHis Tag at the C- terminus. |