Sivelestat sodium tetrahydrate

• Catalog Number: orb1705435
• Category: Small Molecules
• Description: Sivelestat sodium tetrahydrate
• CAS Number: 201677-61-4
• Purity: 99.64%
• MW: 528.51
• SMILES: O=C(CNC(C1=C(NS(=O)(C2=CC=C(C=C2)OC(C(C)(C)C)=O)=O)C=CC=C1)=O)[O-].[Na+].O.O.O.O
• Formula: C₂₀H₂₉N₂NaO₁₁S
• Biological Activity: Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.