Siglec-9 Protein, Human, Recombinant (His & Avi), Biotinylated

• Catalog Number: orb1960599
• Category: Proteins
• Description: Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells. Aberrant glycosylation occurs in essentially all types of cancers and results in increased sialylation. Thus, when the mucin MUC1 is expressed on cancer cells, it is decorated by multiple short, sialylated O-linked glycans (MUC1-ST). Siglec-9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.9 kDa and the accession number is Q9Y336-1.
• Tag: C-His-Avi
• Purity: 98.00%
• MW: 38.9 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
• UniProt ID: Q9Y336
• Expression System: HEK293 Cells
• Biological Origin: Human
• Biological Activity: Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells. Aberrant glycosylation occurs in essentially all types of cancers and results in increased sialylation. Thus, when the mucin MUC1 is expressed on cancer cells, it is decorated by multiple short, sialylated O-linked glycans (MUC1-ST). Siglec-9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.9 kDa and the accession number is Q9Y336-1.
• Expression Region: Gln18-Gly348
• Storage: -20°C
• Note: For research use only
• Application notes: Reconstitute the lyophilized protein in 25mM MES, 150 mM NaCl (pH 5.5). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
• Expiration Date: 6 months from date of receipt.