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Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
Catalog Number: orb1960652
| Catalog Number | orb1960652 |
|---|---|
| Category | Proteins |
| Description | Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.7 kDa and the accession number is A7E1W8-1. |
| Tag | C-His |
| Purity | 98.00% |
| MW | 26.7 kDa (predicted). Due to glycosylation, the protein migrates to 35-43 kDa based on Tris-Bis PAGE result. |
| UniProt ID | A7E1W8 |
| Expression System | HEK293 Cells |
| Biological Origin | Mouse |
| Biological Activity | Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.7 kDa and the accession number is A7E1W8-1. |
| Expression Region | Arg24-Thr262 |
| Storage | -20°C |
| Note | For research use only |
| Application notes | 0 |
| Expiration Date | 6 months from date of receipt. |
