SIAE Protein, Human, Recombinant (His)

Catalog Number: orb1956742

Catalog Number	orb1956742
Category	Small Molecules
Description	SIAE Protein, Human, Recombinant (His)
Purity	98.00%
MW	Approxiamtely 57.4 kDa
Biological Activity	Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of this enzyme class is N-acyl-O-acetylneuraminate O-acetylhydrolase. Other names in common use include N-acetylneuraminate acetyltransferase, sialate 9(4)-O-acetylesterase, and sialidase. Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Defects in Sialate O-acetylesterase are a cause of autoimmune disease type 6 (AIS6). Individuals manifesting susceptibility to autoimmune disease type 6 can suffer from juvenile idiopathic arthritis, rheumatoid arthritis, multiple sclerosis, Sjogren syndrome, systemic lupus erythematosus, type 1 diabetes, ulcerative colitis, and Crohn disease.
Note	For research use only
Expiration Date	12 months from date of receipt.

Recombinant Human SIAE Protein, His Tag [orb1551647]
Purity:
≥90% as determined by SDS-PAGE
Source:
This protein contains the human SIAE(Ile24-Lys523) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Sizes Available: 100 μg, 50 μg
Human SIAE protein (C-His) [orb312013]
Source:
Human Cells
Sizes Available: 50 μg, 1 mg, 500 μg, 10 μg

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human SIAE(Ile24-Lys523) was fused with the C-terminal His Tag and expressed in Mammalian cells.